|
KMID : 1191520180230010023
|
|
Journal of Korean Traditional Oncology
2018 Volume.23 No. 1 p.23 ~ p.32
|
|
|
A Case of Patient with Non-Small Cell Lung Carcinoma Treated with Samchilchoongcho-Jung in Conjunction with Crizotinib
|
|
Ha Su-Jeung
Song Si-Yeon
Park So-Jung
Jun Hyung-Joon
Lee Yeon-Weol
Cho Chong-Kwan
Yoo Hwa-Seung
|
|
|
Abstract
|
|
|
Objective: The purpose of this study is to report the case of a patient with non-small cell lung adenocarcinoma (NSCLC) with anaplastic lymphoma kinase (ALK) mutation treated by Samchilchoongcho-Jung in conjunction with Crizotinib.
Methods: An NSCLC patient diagnosed with multiple pleural and lymph nodes metastasis has been taking Crizotinib (500 mg/day) since January 2014. The patient has been treated with Samchilchoongcho-Jung (1,500 mg/day) since June 2014. The tumor size was measured by computed tomography (CT) and laboratory analysis was conducted. Adverse events were evaluated by the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE), version 5.0.
Results: After combining treatment, stable disease was shown on CT. The tumor marker (CEA, Cyfra 21-1) levels were maintained. NCI-CTCAE 5.0 showed no adverse events.
Conclusion: This case study suggests that Samchilchoongcho-Jung may contribute to tumor response, in conjunction with Crizotinib on the treatment of patients with NSCLC.
|
|
|
KEYWORD
|
|
|
Carcinoma, Non-Small-Cell Lung, crizotinib, anaplastic lymphoma kinase, Samchilchoongcho-Jung
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|
|